Type 3 Diabetes - a new name for Alzheimer's

[Cynthia Prentice]

Among many Alzheimer's researchers there is a new name for Alzheimer's Disease...Type 3 Diabetes, or brain diabetes. Insulin is the big culprit. The prescription for treatment as reported in studies such as the European Journal of Internal Medicine...is not a drug...but is a dietary modification of fewer carbohydrates and more fat and cholesterol in the diet. The go to fat is a saturated medium chain triglyceride oil like coconut oil.

It is not enough to simply switch from white to whole wheat bread...as whole wheat bread has the same glycemic impact on blood sugar as white bread. The recommendation is an overall reduction in carbohydrate and an increase of saturated fat in the diet....and the best time to make this change is in the decades preceding the onset of the disease. The researchers are becoming convinced that like heart disease, cholesterol and brain plaque are repairing agents rather than the actual cause of the disease.

As my home is a lower carbohydrate-higher saturated fat-moderate protein eating family I am very interested in following the research.

Article in Time online with a good introduction http://www.time.com/time/health/arti...673236,00.html

European Journal of Internal Medicine: Nutrition and Alzheimer's disease: The detrimental role of a high carbohydrate diet http://www.lizscript.co.uk/Glyn/EJIM01.pdf

http://www.ncbi.nlm.nih.gov/pubmed/18625458

http://www.amazon.com/Alzheimers-Dis.../dp/1591202930


following video is Dr. Newport's treatment of her husband's alzheimer's.

[Marian Schwaller Carney]

Cynthia, I also learned this recently although I have not read much beyond headlines and abstracts, but it makes complete sense to me. Diabetes affects ones moods and temperament, sometimes profoundly adversely, because of the affect on the brain. We really can no longer shrug off the concern about sugar and simple carbs. Not easy to make the change in eating though, it is a struggle for me.

[John Kennedy]

As the only child of a father who went through the hell of Alzheimers, I found this most interesting.

[Cynthia Prentice]

As the only child of a father who went through the hell of Alzheimers, I found this most interesting.

I have spent the better part of twelve hours today digging through reports and I am very encouraged. I had seen a headline recently that if this last Alzheimer's drug that is in trials doesn't work there probably won't be anymore. Now I understand why. Trials have had to be halted because as plaque was targeted the patients actually became worse. Of course the biggest challenge is that drug companies fund research and since medium chain fatty acids that cause ketone release (the brain uses the ketones as an alternate fuel source instead of glucose) are already available for purchase I'm not sure how long it will take for clinical research to produce numbers. Dr. Richard Veech, senior scientist in the United States National Institutes of Health (NIH) has had difficulty finding funding due to the fact that the treatment is from natural substances.

Dr. Mary Newport (neonatologist who used coconut oil on husband's alzheimers) has written a book: Alzheimer's Disease: What if there was a cure? The story of ketones http://www.amazon.com/Alzheimers-Dis.../dp/1591202930

This is some of the most promising information out there...I'll be watching it closely. My husband has suffered multiple assaults on his brain over the years, four concussions, encephalitis/meningitis, and toxic encephelopathy...he will begin taking coconut oil next week.

[Cynthia Prentice]

Here are the results of Steve Newport's Alzheimer's clock test evaluation. The first picture is before starting coconut oil, the second is two weeks after and the third is five weeks after starting on coconut oil. More info about the clock test here: http://www.alz.org/professionals_and...hers_14306.asp

[Susan Unger]

Quite the difference

[Cynthia Prentice]

I have continued to read about Dr. Mary Newport, neonatologist and medical director of the newborn intensive care unit at Spring Hill Regional Hospital. Here is a brief synopsis of her husbands decline and also links to the scientific research and his case study.

In 2004 Mary's husband Steve, was diagnosed with mild dementia and had a normal MRI. In 2005 he began taking Aricept. In 2006 he began taking Amenda and in 2007 the Aricept was replaced with Exelon. Her husband rapidly declined over the next twelve months. She subscribed to various alerts and checked the website www.clinicaltrials.gov periodically to look for drug studies that Steve may have qualified for. It was in 2008 that she was alerted to research on the potential use of medium chain triglycerides (MCT oil), or ketone bodies (also called ketoacids,) the end product of their metabolism, which may not only treat, but also prevent Alzheimer’s disease. Specifically it was a study of Ketasyn, or AC-1202, that was also recruiting healthy older people to test the tolerability of three different formulations. Investigating further, she learned that this treatment brought about significant improvement over a 90-day period in about half of the subjects who had a certain genetic profile (APOE2 or APOE3.) The APOE4 group remained about the same, whereas the controls (people taking the placebo) continued to show decline. She learned that the promising “ingredient” in Ketasyn is simply MCT oil, and that a dose of 20 grams (about 20 ml or 4 teaspoons) was used to produce these results. The MCT oil that these researchers used was obtained from Stepan Company and consists of primarily 6 and 8 carbon chains, however they state that MCT of any combination of medium chains (6 to 12 carbon chains are medium chain) would also be effective. The research went on to say that MCT oil is derived from coconut and palm (kernal) oil. She calculated the amount of coconut oil it would take to provide the same amount of MCT that was in the study and the case study goes on to share the rest of Steve's story as of 2008. Subsequent to the 2008 case study Steve has continued to improve.

For anyone else interested, here are the links to her husband's case study and her list of scientific references.. The Scientific reference link will download a word file, the 2008 case study is in a pdf file. The 2011 case study is a word file.

Case Study on Steve Newport 2008 (including footnotes): http://www.coconutketones.com/whatifcure.pdf
Updated Case Study 2011: http://www.google.com/url?sa=t&rct=j...TfJwMfFup0wt0g

Scientific references for Ketone research: http://www.coconutketones.com/Ketone...references.doc

[Karen Troxler]

Thanks Cynthia. I haven't read the articles yet, but I plan to do so. Alzheimer's runs in my family. My grandfather had it, though at the time they said he was in his "second childhood." Three of my aunts have it, and at least one of my cousins. I've heard from some sources that it supposedly doesn't run in families, but based on my family's history, I'm not convinced.

[Cynthia Prentice]

Thanks Cynthia. I haven't read the articles yet, but I plan to do so. Alzheimer's runs in my family. My grandfather had it, though at the time they said he was in his "second childhood." Three of my aunts have it, and at least one of my cousins. I've heard from some sources that it supposedly doesn't run in families, but based on my family's history, I'm not convinced.

There are genetic markers that have been identified with Alzheimer's so you are correct in your concern. Even without a family history, the general population has a fifty/fifty chance of developing Alzheimer's by the age of 85.

Alzheimer's Disease Genetics:Fact Sheet http://www.coconutketones.com/pdfs/A...kFactSheet.pdf

[Cynthia Prentice]

It is a big leap for many people to even begin to examine whether or not MTC therapy (medium chain triglycerides found in coconut oil) could impact Alzheimer's through prevention, and halting the progression of those who have it. I understand that. The reaction that some have to this information is almost angry. In some ways I think of Galileo and his belief in a heliocentric solar system.

I was also thinking about another disease that plagued mankind for thousands of years. This disease was cured and prevented without a prescription drug. It was a disease that left untreated was fatal and yet the disease had a simple fix. Here are the symptoms that accompanied the disease.

malaise
lethargy
After 1–3 months, patients develop shortness of breath and bone pain.
skin changes with roughness, easy bruising and petechiae
gum disease
loosening of teeth
poor wound healing
emotional changes
Dry mouth and dry eyes similar to Sjögren's syndrome may occur
In the late stages, jaundice
generalized edema
oliguria (low output of urine)
neuropathy
fever
convulsions
and eventual death are frequently seen.

What was the disease that killed so many over thousands of years? Scurvy. Today scurvy is known to be caused by a nutritional deficiency, but until the isolation of vitamin C and its direct link to scurvy in 1932, numerous theories and treatments were proposed, often on little or no experimental data. This inconsistency is attributed to the lack of vitamin C as a distinct concept, the varying vitamin C content of different foods (notably present in fresh citrus, watercress, and organ meat), and how vitamin C can be destroyed by exposure to air and copper. Part of the confusion came because there were people groups who existed almost exclusively on fresh meat and fat yet these people did not get scury. What was not known is that ascorbic acid (vitamin C) is available in fresh meat...causing the confusion.

Treatment by fresh food, particularly citrus fruit, was periodically implemented, as it had been since antiquity. Documentation goes back at least as far as the 1400's suggesting that scurvy could be cured with citrus fruit. Citrus fruit as a prevention and cure for scurvy was finally proven in 1753 in the first ever clinical trial by Scottish surgeon in the Royal Navy, James Lind, who first proved it could be treated with citrus fruit in experiments he described in his 1753 book, A Treatise of the Scurvy,though his advice was not implemented by the Royal Navy for several decades. The ultimate cause of scurvy was not known until 1932, and treatment was inconsistent, with many ineffective treatments used into the 20th century. In the elapsed time between the proposed cure and clinical trials...millions died from this preventable disease. Let's hope and pray that it does not take hundreds of years between the discovery of what can help prevent and treat Alzheimer's Disease, and its proof through clinically proven medical trials. What a tragedy that would be for our nation and the 15,000,000 people projected to have Alzheimer's disease by 2050.

After pouring over the science behind ketone therapy, it is my belief that Dr. Mary Newport, author of Alzheimer's Disease: What if there was a Cure?, is one who like the early doctors who treated scurvy, was proactive and based on research she discovered embraced a very real treatment of Alzheimer's. Had she waited for this country's mammoth medical machine to catch up and confirm the validity of MCT's as an accepted treatment her husband's brain would almost certainly be at a place where he was no longer with her.

If one of you on this thread reads it...I'll look forward to the discussion it generates.

Link: http://www.amazon.com/Alzheimers-Dis...ory+of+ketones